Natural killer nk cells are innate immune cells endowed with potent cytolytic activity against tumors and meanwhile act as regulatory cells for the immune system.
The application of natural killer cell immunotherapy for the treatment of cancer.
Despite reports of clinical efficacy a number of factors limit the application of nk cell immunotherapy for the treatment of cancer such as the failure of infused nk cells to expand and persist.
Cancer immunotherapy has been firmly established as a new milestone for cancer therapy with the development of multiple immune cells as therapeutic tools.
Engineering natural killer cells for cancer immunotherapy the past several years have seen tremendous advances in the engineering of immune effector cells as therapy for cancer.